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AG Molekulare Schmerzforschung - Publikationen

Ausgewählte Originalarbeiten

Mambretti EM, Kistner K, Mayer S, Massotte D, Kieffer BL, Hoffmann C, Reeh PW, Brack A, Asan E, Rittner HL
“Functional and structural characterization of axonal opioid receptors as targets for analgesia”
Mol Pain (2016) im Druck
Impact Factor [3,7]

Yang S, Krug SM, Heitmann J, Hu L, Reinhold AK, Bosten J, Sommer C, Fromm M, Brack A, Rittner HL
„Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183 triggered opening of the blood-nerve barrier “
Biomaterials (2016) 82:20-33
Impact Factor [8,6]

Doppler K, Rittner HL, Deckart M, Sommer C.
“Reduced dermal nerve fiber diameter in skin biopsies of patients with fibromyalgia.”
Pain (2015) 156(11):2319-25
Impact Factor [5,2]

Reinhold AK, Batti L, Bilbao D, Buness A, Rittner HL, Heppenstall PA
“Differential transcriptional profiling of damaged and intact adjacent dorsal root ganglia neurons in neuropathic pain.”
PLoS One (2015) 10(4):e0123342
Impact Factor [3,2]

Dabrowski S, Staat C, Haseloff R, Sauer RS, Rittner HL, Blasig IE
“Redox-sensitive structure and function of the first extracellular loop of the cell-cell contact protein claudin-1 – lessons from molecular structure to animal”
Antioxidants & Redox Signaling (2015) 22(1):1-14
Impact Factor [7,4]

Sauer RS, Krug S, Hackel D, Staat C, Günther R, Konasin N, Yang S, Niedermirtl B, Bosten J, Doppler K, Sommer C, Blasig IE Brack, A, Rittner HL
“Safety, efficacy, and molecular mechanism of claudin-1-specific peptides to enhance blood-nerve-barrier permeability”
J Controlled Release (2014) 185:88-98
Impact Factor 7,7

Wang Y, Hackel D, Peng F, Rittner HL
„Long-term antinociception by electroacupuncture is mediated via peripheral opioid receptors in free-moving rats with inflammatory hyperalgesia”
Eur J Pain (2013) (9):897-910
Impact Factor 3,9

Hackel D, Pflücke D, Neumann A, Viebahn J, Wischmeyer E, Roewer N, Brack A, Rittner HL
„The connection of monocytes and reactive oxygen species in pain.”
PLoS One (2013) 8(5):e63564
Impact Factor 4,1

Pflücke D, Hackel D, Neumann A, Partheil A, Brack A, Rittner HL
„The molecular link between C-C-chemokine ligand 2 (CCL2)-induced leukocyte recruitment and hyperalgesia.”
J Pain (2013) 14(9):897-910
Impact Factor 4,8

Hackel D, Krug SM, Sauer RS, Mousa SA, Böcker A, Pflücke D, Wrede EJ, Kistner K, Hoffmann T, Niedermirtl B, Sommer C, Bloch L, Huber O, Blasig IE, Amasheh S, Reeh PW, Fromm M, Brack A, Rittner HL „Transient opening of the perineurial barrier for analgesic drug delivery. ”
Proc. Natl. Acad. Sci. USA (2012) 109(29):E2018-27
Impact Factor 9,8

Zwanziger D, Hackel D, Staat C, Böcker A, Brack A, Beyermann M, Rittner HL, Blasig IE „A peptidomimetic tight junction modulator to improve regional analgesia. ”
Mol. Pharmaceut. (2012) 9(6):1785-94
Impact Factor 5,4

Rittner HL, Amasheh S, Moshourab R, Hackel D, Yamdeu RS, Fromm M, Stein C, Brack A „Modulation of tight junction proteins in the perineurium to facilitate peripheral opioid analgesia. ”
Anesthesiology (2012) 116(6): 1323-1334
Impact Factor 5,2

Hackel D, Stolz A, Mousa SA, Brack A, Rittner H
„Recruitment of opioid peptide-containing neutrophils is independent of formyl peptide receptors.”
J Neuroimmunol (2011) 230:65-73
Impact Factor 2,8

Rittner HL, Hackel D, Voigt P, Mousa SA, Stolz A, Schaefer M, Schäfer M, Stein C, Brack A „Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils”
PLoS Pathogens (2009) 5(4):e1000362
Impact Factor 9,0

Labuz D, Schmidt Y, Schreiter A, Rittner HL, Mousa SA, Machelska H
„Immune cell derived opioid protect against neuropathic pain”
J Clin Invest (2009) 119:278-86
Impact Factor 16,6

Zöllner C, Mousa SA, Fischer O, Rittner HL, Shaqura M, Brack A, Urban F, Shakibaei M, Stein C, Schäfer M
„Inflammatory pain prevents the development of tolerance at peripheral µ-opioid receptors”
J Clin Invest (2008) 118: 1065-73
Impact Factor 16,9

Ausgewählte Übersichtsarbeiten

Hackel D, Brack A, Fromm M, Rittner H Modulation of tight junction proteins in the perineurium for regional pain control. Ann. N.Y. Acad. Sci. (2012) 257(1):199-206.
IF 2,8

Rittner HL, Roewer N, Brack A “The clinical (ir)relevance of opioid-induced immune suppression.” Curr Opin Anaesthesiol. 2010 im DruckSchäfer M, Keilig S, Brack A, Kranke P „[Opioid induced cough: Do we know its pathophysiology and can it be eliminated?]”Anasthesiol Intensivmed Notfallmed Schmerzther. (2010) 45(3): 170-3

Rittner HL, Kranke P, Schäfer M, Roewer N, Brack A „Was lernen wir aus dem Fall Scott Reuben? Wissenschaftliches Fehlverhalten in der Anästhesiologie”
Anaesthesist (2009) 58(12): 1199-209

Rittner HL, Brack A, Stein C „Pain and Immune System
Br J Anaesthesia (2008) 101: 40-4

Rittner HL, Brack A, Stein C „The other side of the medal: how chemokines promote analgesia”
Neurosci Letters (2008) 437: 203-8

Rittner HL, Brack A „Leukocytes as mediators of pain and analgesia”
Curr Rheumatology Reports (2007) 9:503-10

Ausgewählte Buchkapitel

Brack A, Rittner HL  „Nicht-Opioide”
in Standl T, Schulte am Esch J, Treede RD, Schäfer M, Bardenheuer HJ (Hrsg.) AINS Lehrbuch „Schmerztherapie” 2. Auflage, Thieme Verlag (2010) 106-112

Hackel D, Brack A, Rittner HL  „Leukocytes as mediators of pain and analgesia“
in Berczi I, Szentivanyi A (Editors-in-Chief) “Neuroimmune Biology”, Arnason BG (Volume Editor) „The brain and host defense”, Volume 9, 1st edition, Elsevier (2010) 237-50

Brack A, Schäfer M „Analgetika”
in Krier C, Kochs E, Spies C und Adams A (Hrsg.)
AINS Lehrbuch „Anästhesiologie” 2. Auflage, Thieme Verlag; (2009) 89 - 104

Brack A, Schäfer M „Nichtopioid-Analgetika”
in Rossaint R, Werner C, Zwißler B (Hrsg.) „Die Anästhesiologie” 2. Auflage, Springer Verlag Berlin, Heidelberg, New York (2008) 274-296

Rittner HL, Machelska H, Stein C  „Immune system, pain and analgesia“ in Basbaum, Kaneko, Shepherd, Westheimer: The Senses - a comprehensive reference (2008), Volume 5: Pain (eds Basbaum, Bushnell, Julius), Academic Press, Oxford

Brack A, Stein C, Schaible HG
„Periphere und zentrale Mechanismen des Entzündungsschmerzes”
in Straub RH (Hrsg.) „Lehrbuch der klinischen Pathophysiologie multifaktorieller Erkran-kungen“ Band I „Physiologische Grundlagen“ Vandenhoek & Ruprecht Göttingen (2006) 183-192